Gibberellin Signalling Group - Inhibition of RNA degradation

Journal article

Putri Prasetyaningrum, S. Litthauer, Franco Vegliani, M. Battle, Matthew William Wood, Xinmeng Liu, C. Dickson, M. Jones
Journal of Experimental Botany, 2023

Semantic Scholar DOI PubMedCentral PubMed

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APA Click to copy
Prasetyaningrum, P., Litthauer, S., Vegliani, F., Battle, M., Wood, M. W., Liu, X., … Jones, M. (2023). Inhibition of RNA degradation integrates the metabolic signals induced by osmotic stress into the Arabidopsis circadian system. Journal of Experimental Botany.

Chicago/Turabian Click to copy
Prasetyaningrum, Putri, S. Litthauer, Franco Vegliani, M. Battle, Matthew William Wood, Xinmeng Liu, C. Dickson, and M. Jones. “Inhibition of RNA Degradation Integrates the Metabolic Signals Induced by Osmotic Stress into the Arabidopsis Circadian System.” Journal of Experimental Botany (2023).

MLA Click to copy
Prasetyaningrum, Putri, et al. “Inhibition of RNA Degradation Integrates the Metabolic Signals Induced by Osmotic Stress into the Arabidopsis Circadian System.” Journal of Experimental Botany, 2023.

BibTeX Click to copy

@article{putri2023a,
  title = {Inhibition of RNA degradation integrates the metabolic signals induced by osmotic stress into the Arabidopsis circadian system},
  year = {2023},
  journal = {Journal of Experimental Botany},
  author = {Prasetyaningrum, Putri and Litthauer, S. and Vegliani, Franco and Battle, M. and Wood, Matthew William and Liu, Xinmeng and Dickson, C. and Jones, M.}
}

Abstract

Abstract The circadian clock system acts as an endogenous timing reference that coordinates many metabolic and physiological processes in plants. Previous studies have shown that the application of osmotic stress delays circadian rhythms via 3ʹ-phospho-adenosine 5ʹ-phosphate (PAP), a retrograde signalling metabolite that is produced in response to redox stress within organelles. PAP accumulation leads to the inhibition of exoribonucleases (XRNs), which are responsible for RNA degradation. Interestingly, we are now able to demonstrate that post-transcriptional processing is crucial for the circadian response to osmotic stress. Our data show that osmotic stress increases the stability of specific circadian RNAs, suggesting that RNA metabolism plays a vital role in circadian clock coordination during drought. Inactivation of XRN4 is sufficient to extend circadian rhythms as part of this response, with PRR7 and LWD1 identified as transcripts that are post-transcriptionally regulated to delay circadian progression.